| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_02505 | ISM_04555 | COG0287 Prephenate dehydrogenase. | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | 0.402 |
| ISM_02505 | ISM_12920 | COG0287 Prephenate dehydrogenase. | COG0460 Homoserine dehydrogenase. | 0.614 |
| ISM_03915 | ISM_04555 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | 0.423 |
| ISM_03915 | ISM_16955 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.997 |
| ISM_04545 | ISM_04550 | Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase. | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | 0.823 |
| ISM_04545 | ISM_04555 | Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase. | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | 0.727 |
| ISM_04550 | ISM_04545 | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase. | 0.823 |
| ISM_04550 | ISM_04555 | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | 0.768 |
| ISM_04555 | ISM_02505 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | COG0287 Prephenate dehydrogenase. | 0.402 |
| ISM_04555 | ISM_03915 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.423 |
| ISM_04555 | ISM_04545 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase. | 0.727 |
| ISM_04555 | ISM_04550 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | 0.768 |
| ISM_04555 | ISM_04560 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. | 0.513 |
| ISM_04555 | ISM_04565 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | Efflux transporter, RND family protein, MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.414 |
| ISM_04555 | ISM_04570 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | Transporter, AcrB/AcrD/AcrF family protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.402 |
| ISM_04555 | ISM_05940 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein. | 0.470 |
| ISM_04555 | ISM_12920 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | COG0460 Homoserine dehydrogenase. | 0.420 |
| ISM_04555 | ISM_16955 | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.423 |
| ISM_04560 | ISM_04555 | Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. | Transporter, putative; COG0477 Permeases of the major facilitator superfamily. | 0.513 |
| ISM_04560 | ISM_04565 | Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. | Efflux transporter, RND family protein, MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.717 |