Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_04555Transporter, putative; COG0477 Permeases of the major facilitator superfamily. (386 aa)    
Predicted Functional Partners:
ISM_04550
DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.
     
 0.768
ISM_04545
Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase.
     
 0.727
ISM_04560
Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators.
       0.513
ISM_05940
Hypothetical protein.
  
   0.470
ISM_03915
2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
     
  0.423
ISM_16955
Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
     
  0.423
ISM_12920
COG0460 Homoserine dehydrogenase.
  
  0.420
ISM_04565
Efflux transporter, RND family protein, MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.414
ISM_02505
COG0287 Prephenate dehydrogenase.
  
  
  0.402
ISM_04570
Transporter, AcrB/AcrD/AcrF family protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.402
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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