Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
ISM_04570Transporter, AcrB/AcrD/AcrF family protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1016 aa)    
Predicted Functional Partners:
ISM_04565
Efflux transporter, RND family protein, MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.985
ISM_08260
Type I secretion membrane fusion protein, HlyD family protein; COG0845 Membrane-fusion protein.
  
 0.821
ISM_08225
HlyD family secretion protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.820
ISM_05600
Type I secretion outer membrane protein, TolC family protein; COG1538 Outer membrane protein.
 
 0.818
ISM_00700
COG1538 Outer membrane protein.
 
 0.797
ISM_06300
Cation/multidrug efflux pump, membrane-fusion protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.792
ISM_09391
Efflux transporter, RND family protein, MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.792
ISM_17455
COG1538 Outer membrane protein.
  
 0.713
ISM_04560
Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators.
 
     0.686
yajC
Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
    
 
 0.576
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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