Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_04625Glyoxalase family protein; COG0346 Lactoylglutathione lyase and related lyases. (124 aa)    
Predicted Functional Partners:
ISM_04630
Redox-sensitive transcriptional activator SoxR; COG0789 Predicted transcriptional regulators.
 
     0.852
ISM_02775
D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.
    
  0.542
gloB
Putative hydroxyacylglutathione hydrolase (glyoxalase II) (GLX II)protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
     
  0.541
ISM_04635
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
    
  0.520
ISM_10720
Hypothetical protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
    
  0.470
ISM_04615
COG1981 Predicted membrane protein.
       0.451
ISM_04620
COG3336 Predicted membrane protein.
       0.451
ISM_06365
COG0346 Lactoylglutathione lyase and related lyases.
    
 0.435
ISM_13160
Lactoylglutathione lyase, putative; COG0346 Lactoylglutathione lyase and related lyases.
    
 0.435
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.401
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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