| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_04390 | ISM_04640 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.542 |
| ISM_04390 | ISM_04820 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.532 |
| ISM_04390 | ISM_12595 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.560 |
| ISM_04635 | ISM_04640 | COG0436 Aspartate/tyrosine/aromatic aminotransferase. | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.505 |
| ISM_04635 | ISM_04820 | COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.525 |
| ISM_04635 | ISM_12595 | COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.513 |
| ISM_04640 | ISM_04390 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.542 |
| ISM_04640 | ISM_04635 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 0.505 |
| ISM_04640 | ISM_04820 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.645 |
| ISM_04640 | ISM_07810 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Hydantoinase/oxoprolinase family protein; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. | 0.568 |
| ISM_04640 | ISM_11170 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | acyl-CoA synthetase, putative; COG1042 Acyl-CoA synthetase (NDP forming). | 0.551 |
| ISM_04640 | ISM_12595 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.652 |
| ISM_04640 | ISM_13445 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Hypothetical protein. | 0.474 |
| ISM_04640 | ISM_13450 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Corrinoid methyltransferase protein, putative; COG5012 Predicted cobalamin binding protein. | 0.569 |
| ISM_04640 | ISM_15125 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Hypothetical protein. | 0.522 |
| ISM_04640 | ISM_16340 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | COG3894 Uncharacterized metal-binding protein. | 0.516 |
| ISM_04820 | ISM_04390 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.532 |
| ISM_04820 | ISM_04635 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 0.525 |
| ISM_04820 | ISM_04640 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.645 |
| ISM_04820 | ISM_12595 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.878 |