STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_04760COG0810 Periplasmic protein TonB, links inner and outer membranes. (463 aa)    
Predicted Functional Partners:
ISM_04765
HemY domain protein; COG3071 Uncharacterized enzyme of heme biosynthesis.
 
   
 0.908
ISM_04755
Hypothetical protein.
 
     0.858
tsaD
O-sialoglycoprotein endopeptidase, putative; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
       0.641
ISM_04735
Hypothetical protein.
       0.639
ISM_04740
YCII-related domain protein; COG2350 Uncharacterized protein conserved in bacteria.
       0.629
gpsA
COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
       0.621
ISM_09366
Possible peptidoglycan binding protein; COG1652 Uncharacterized protein containing LysM domain.
  
    0.599
ISM_06825
Hypothetical protein; COG3893 Inactivated superfamily I helicase.
 
     0.545
ISM_02205
MORN repeat protein; COG4642 Uncharacterized protein conserved in bacteria.
  
     0.516
ISM_15050
COG2825 Outer membrane protein.
  
     0.515
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.