Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_04765HemY domain protein; COG3071 Uncharacterized enzyme of heme biosynthesis. (525 aa)    
Predicted Functional Partners:
ISM_04760
COG0810 Periplasmic protein TonB, links inner and outer membranes.
 
     0.889
ISM_04755
Hypothetical protein.
 
     0.743
ISM_11710
Hypothetical protein; COG0500 SAM-dependent methyltransferases.
  
     0.700
ISM_09326
Putative cytochrome c-type biogenesis protein, cycH; COG4235 Cytochrome c biogenesis factor.
  
     0.689
ISM_06825
Hypothetical protein; COG3893 Inactivated superfamily I helicase.
  
     0.674
ISM_08625
Hypothetical protein.
  
  
 0.655
ISM_04575
Hypothetical protein; COG1562 Phytoene/squalene synthetase.
  
     0.628
ftsQ
Cell division protein ftsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
  
     0.621
ISM_09806
Hypothetical protein.
  
     0.617
ISM_02275
Hypothetical protein; COG1466 DNA polymerase III, delta subunit.
 
     0.605
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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