| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_04820 | ISM_06100 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.958 |
| ISM_04820 | ISM_06815 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | 0.948 |
| ISM_04820 | ISM_07105 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Iron-sulfur cluster-binding protein; COG0633 Ferredoxin. | 0.865 |
| ISM_04820 | ISM_07435 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | COG3118 Thioredoxin domain-containing protein. | 0.948 |
| ISM_04820 | ISM_07825 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Oxidoreductase, FMN-binding/pyridine nucleotide-disulfideoxidoreductase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.906 |
| ISM_04820 | ISM_08180 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.905 |
| ISM_04820 | ISM_08600 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Thiol:disulfide interchange protein, putative; COG0526 Thiol-disulfide isomerase and thioredoxins. | 0.946 |
| ISM_04820 | ISM_09185 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Thiol-specific antioxidant protein; COG0450 Peroxiredoxin. | 0.965 |
| ISM_04820 | ISM_11325 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily protein; COG0526 Thiol-disulfide isomerase and thioredoxins. | 0.946 |
| ISM_04820 | ISM_12595 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.878 |
| ISM_06100 | ISM_04820 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.958 |
| ISM_06100 | ISM_06815 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | 0.722 |
| ISM_06100 | ISM_07435 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG3118 Thioredoxin domain-containing protein. | 0.722 |
| ISM_06100 | ISM_07825 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Oxidoreductase, FMN-binding/pyridine nucleotide-disulfideoxidoreductase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.953 |
| ISM_06100 | ISM_08180 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.405 |
| ISM_06100 | ISM_09185 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Thiol-specific antioxidant protein; COG0450 Peroxiredoxin. | 0.480 |
| ISM_06100 | ISM_12595 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.953 |
| ISM_06815 | ISM_04820 | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.948 |
| ISM_06815 | ISM_06100 | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.722 |
| ISM_06815 | ISM_07825 | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | Oxidoreductase, FMN-binding/pyridine nucleotide-disulfideoxidoreductase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.449 |