STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_04845ATP-binding region, ATPase-like:Histidine kinase, HAMPregion:Histidine kinase A, N-terminal; COG0642 Signal transduction histidine kinase. (655 aa)    
Predicted Functional Partners:
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 
0.982
ISM_04850
COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
 0.946
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 
0.871
ISM_04775
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
 
0.784
ISM_05545
Histidine kinase/response regulator hybrid protein; COG2202 FOG: PAS/PAC domain.
  
 0.772
ISM_01565
Response regulator receiver protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.
  
 0.694
ISM_05855
Possible FlgD protein; Required for flagellar hook formation. May act as a scaffolding protein.
   
    0.647
ISM_12885
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
 
0.646
ISM_04780
PAS; COG0642 Signal transduction histidine kinase.
 
 
0.644
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
  
 0.628
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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