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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_04850COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (452 aa)    
Predicted Functional Partners:
ISM_04845
ATP-binding region, ATPase-like:Histidine kinase, HAMPregion:Histidine kinase A, N-terminal; COG0642 Signal transduction histidine kinase.
 
 0.946
ISM_16640
Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific.
 0.893
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 
 0.873
ISM_00650
Transcriptional regulatory protein; COG3284 Transcriptional activator of acetoin/glycerol metabolism.
 
     0.785
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
 
 0.753
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 
 0.745
ISM_11180
C4-dicarboxylate transport sensor protein dctB; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system.
 0.729
ISM_16630
Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.
 
 0.703
ISM_12905
Multi-sensor Signal Transduction Histidine Kinase; COG2202 FOG: PAS/PAC domain.
 
 
 0.682
ISM_01205
Sensor histidine kinase; COG0591 Na+/proline symporter.
   
 0.644
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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