Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_05025COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (126 aa)    
Predicted Functional Partners:
hisD-3
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
    0.639
ISM_05015
Gluconate 5-dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
       0.601
ISM_05020
Sorbitol dehydrogenase, putative; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.
  
    0.601
ISM_03500
COG0350 Methylated DNA-protein cysteine methyltransferase.
  
    0.533
ISM_05005
Transcriptional regulator, LacI family protein; COG1609 Transcriptional regulators.
       0.410
groEL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.409
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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