STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_05330Hypothetical protein; COG5387 Chaperone required for the assembly of the mitochondrial F1-ATPase. (236 aa)    
Predicted Functional Partners:
ISM_05340
Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
 
     0.895
ISM_05335
HAD-superfamily hydrolase, subfamily IA, variant 1; COG0546 Predicted phosphatases.
       0.853
crcB
CrcB-like protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.835
atpA
ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
    
 
 0.719
atpD
ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
    
 
 0.674
ISM_01300
COG3761 NADH:ubiquinone oxidoreductase 17.2 kD subunit.
  
     0.642
ISM_06570
COG0500 SAM-dependent methyltransferases.
  
     0.592
ISM_00380
Cobalt chelatase, pCobT subunit; COG0436 Aspartate/tyrosine/aromatic aminotransferase.
  
     0.581
ISM_14000
Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
     0.559
ISM_00345
DnaJ domain protein; COG2214 DnaJ-class molecular chaperone.
  
 
 
 0.538
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: medium (44%) [HD]