STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_05335HAD-superfamily hydrolase, subfamily IA, variant 1; COG0546 Predicted phosphatases. (228 aa)    
Predicted Functional Partners:
ISM_02775
D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.
    
 0.913
ISM_09020
Glycolate oxidase, iron-sulfur subunit; COG0247 Fe-S oxidoreductase.
    
 0.909
ISM_09025
Putative glycolate oxidase subunit protein; COG0277 FAD/FMN-containing dehydrogenases.
    
 0.909
ISM_09030
Glycolate oxidase, GlcD subunit; COG0277 FAD/FMN-containing dehydrogenases.
    
 0.909
ISM_11130
D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.908
ISM_14455
COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.908
ISM_05340
Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
    0.871
crcB
CrcB-like protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
  
    0.855
ISM_05330
Hypothetical protein; COG5387 Chaperone required for the assembly of the mitochondrial F1-ATPase.
       0.853
ISM_12005
HAD-superfamily hydrolase, subfamily IA, variant 1 family protein; COG0546 Predicted phosphatases.
  
  
  0.826
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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