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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_05365Pyridine nucleotide-disulphide oxidoreductase family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. (402 aa)    
Predicted Functional Partners:
ISM_06180
Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein.
  
 0.995
ISM_07715
Formate dehydrogenase, alpha subunit; COG3383 Uncharacterized anaerobic dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.972
ISM_05360
Methyltransferase, putative; COG0742 N6-adenine-specific methylase.
       0.853
ISM_07105
Iron-sulfur cluster-binding protein; COG0633 Ferredoxin.
 
 
 0.836
ISM_08180
Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
  
 
 0.818
ISM_04820
Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 
 0.786
ISM_15735
COG0155 Sulfite reductase, beta subunit (hemoprotein).
  
 0.691
ISM_15725
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
  
 0.678
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
  
  
 0.667
ISM_12965
COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.667
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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