| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_01360 | ISM_03735 | ISM_01360 | ISM_03735 | Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Putative ATP-dependent RNA helicase protein; COG0513 Superfamily II DNA and RNA helicases. | 0.631 |
| ISM_01360 | ISM_14115 | ISM_01360 | ISM_14115 | Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | ATP-dependent RNA helicase, DEAD/DEAH box family protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.631 |
| ISM_01360 | ISM_17200 | ISM_01360 | ISM_17200 | Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.631 |
| ISM_01360 | nnrD | ISM_01360 | ISM_05415 | Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.781 |
| ISM_03735 | ISM_01360 | ISM_03735 | ISM_01360 | Putative ATP-dependent RNA helicase protein; COG0513 Superfamily II DNA and RNA helicases. | Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.631 |
| ISM_03735 | ISM_11665 | ISM_03735 | ISM_11665 | Putative ATP-dependent RNA helicase protein; COG0513 Superfamily II DNA and RNA helicases. | Hydrolase, NUDIX family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.631 |
| ISM_03735 | ISM_12345 | ISM_03735 | ISM_12345 | Putative ATP-dependent RNA helicase protein; COG0513 Superfamily II DNA and RNA helicases. | RNA methyltransferase, TrmH family, group 3; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.717 |
| ISM_03735 | groEL | ISM_03735 | ISM_05755 | Putative ATP-dependent RNA helicase protein; COG0513 Superfamily II DNA and RNA helicases. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.655 |
| ISM_03735 | nnrD | ISM_03735 | ISM_05415 | Putative ATP-dependent RNA helicase protein; COG0513 Superfamily II DNA and RNA helicases. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.808 |
| ISM_03735 | rppH | ISM_03735 | ISM_02440 | Putative ATP-dependent RNA helicase protein; COG0513 Superfamily II DNA and RNA helicases. | Hydrolase, NUDIX family protein of the NudH subfamily; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.670 |
| ISM_06040 | nnrD | ISM_06040 | ISM_05415 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.797 |
| ISM_06840 | nnrD | ISM_06840 | ISM_05415 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.819 |
| ISM_11665 | ISM_03735 | ISM_11665 | ISM_03735 | Hydrolase, NUDIX family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Putative ATP-dependent RNA helicase protein; COG0513 Superfamily II DNA and RNA helicases. | 0.631 |
| ISM_11665 | ISM_14115 | ISM_11665 | ISM_14115 | Hydrolase, NUDIX family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | ATP-dependent RNA helicase, DEAD/DEAH box family protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.631 |
| ISM_11665 | ISM_17200 | ISM_11665 | ISM_17200 | Hydrolase, NUDIX family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.631 |
| ISM_11665 | nnrD | ISM_11665 | ISM_05415 | Hydrolase, NUDIX family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.807 |
| ISM_12345 | ISM_03735 | ISM_12345 | ISM_03735 | RNA methyltransferase, TrmH family, group 3; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Putative ATP-dependent RNA helicase protein; COG0513 Superfamily II DNA and RNA helicases. | 0.717 |
| ISM_12345 | ISM_14115 | ISM_12345 | ISM_14115 | RNA methyltransferase, TrmH family, group 3; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | ATP-dependent RNA helicase, DEAD/DEAH box family protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.717 |
| ISM_12345 | ISM_17200 | ISM_12345 | ISM_17200 | RNA methyltransferase, TrmH family, group 3; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.717 |
| ISM_12345 | nnrD | ISM_12345 | ISM_05415 | RNA methyltransferase, TrmH family, group 3; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.800 |
