Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_05455COG1309 Transcriptional regulator. (212 aa)    
Predicted Functional Partners:
ISM_05450
Putative branched-chain amino acid-binding protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.
       0.565
ISM_08180
Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
 
 
 0.531
ISM_05460
COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold.
       0.470
ISM_02060
enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase.
 
 
 0.466
ISM_05430
COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.
       0.441
ISM_05435
Leucine/isoleucine/valine transport system ATP-binding protein; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.
       0.441
ISM_05440
COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.
       0.441
ISM_05445
Putative ABC transporter, permease protein; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.
       0.441
ISM_05425
Peptidase, M19 family protein; COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog.
       0.431
ISM_05465
Probable macrophage infectivity potentiator protein Mip; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
       0.430
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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