Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_05465Probable macrophage infectivity potentiator protein Mip; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (181 aa)    
Predicted Functional Partners:
ISM_05460
COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold.
 
     0.732
ISM_05470
Putative ABC transport system, solute-binding protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.
       0.596
ISM_05455
COG1309 Transcriptional regulator.
       0.430
pcaC
4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
    
 0.428
ISM_12060
COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
    
 0.428
ISM_14370
4-carboxymuconolactone decarboxylase, putative; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
    
 0.428
ISM_09185
Thiol-specific antioxidant protein; COG0450 Peroxiredoxin.
  
  
 0.423
ISM_05495
COG1309 Transcriptional regulator.
       0.421
ISM_05475
COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.
       0.418
ISM_05480
COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.
       0.418
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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