STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_05515COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (224 aa)    
Predicted Functional Partners:
ISM_05520
COG0642 Signal transduction histidine kinase.
 0.985
ISM_04775
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
 0.969
ISM_05545
Histidine kinase/response regulator hybrid protein; COG2202 FOG: PAS/PAC domain.
 
 0.952
ISM_16105
Hypothetical protein.
   
 0.928
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
0.924
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
  
 0.913
ISM_12905
Multi-sensor Signal Transduction Histidine Kinase; COG2202 FOG: PAS/PAC domain.
 0.910
ISM_06040
Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
   
 
 0.905
ISM_12885
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
  0.892
ISM_04780
PAS; COG0642 Signal transduction histidine kinase.
 
  0.866
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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