STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_05545Histidine kinase/response regulator hybrid protein; COG2202 FOG: PAS/PAC domain. (779 aa)    
Predicted Functional Partners:
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 0.999
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 0.997
ISM_01565
Response regulator receiver protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.
 
 0.994
ISM_06625
Response regulator; COG0784 FOG: CheY-like receiver.
 
 0.994
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
 
 0.985
ISM_07425
Putative two-component system sensor histidine kinase; COG2203 FOG: GAF domain.
 
 0.985
ISM_05245
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.981
ISM_05685
Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
 0.979
ISM_11995
Diguanylate cyclase, putative/response regulator; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
  
 0.961
ISM_03770
Hypothetical protein; COG2198 FOG: HPt domain.
  
 0.959
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.