STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_05545Histidine kinase/response regulator hybrid protein; COG2202 FOG: PAS/PAC domain. (779 aa)    
Predicted Functional Partners:
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 0.999
ISM_06625
Response regulator; COG0784 FOG: CheY-like receiver.
  
 0.987
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 0.982
ISM_07425
Putative two-component system sensor histidine kinase; COG2203 FOG: GAF domain.
 
 0.982
ISM_01565
Response regulator receiver protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.
 
 0.971
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
 
 0.964
ISM_12905
Multi-sensor Signal Transduction Histidine Kinase; COG2202 FOG: PAS/PAC domain.
 
0.956
ISM_01205
Sensor histidine kinase; COG0591 Na+/proline symporter.
  
 0.952
ISM_05685
Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
 
 0.930
ISM_05265
Diguanylate cyclase, putative; COG2200 FOG: EAL domain.
  
 0.915
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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