| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_03735 | ISM_05565 | ISM_03735 | ISM_05565 | Putative ATP-dependent RNA helicase protein; COG0513 Superfamily II DNA and RNA helicases. | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | 0.487 |
| ISM_05560 | ISM_05565 | ISM_05560 | ISM_05565 | Glycosyl transferase, group 2 family protein; COG0463 Glycosyltransferases involved in cell wall biogenesis. | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | 0.691 |
| ISM_05560 | ISM_05570 | ISM_05560 | ISM_05570 | Glycosyl transferase, group 2 family protein; COG0463 Glycosyltransferases involved in cell wall biogenesis. | Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.508 |
| ISM_05565 | ISM_03735 | ISM_05565 | ISM_03735 | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | Putative ATP-dependent RNA helicase protein; COG0513 Superfamily II DNA and RNA helicases. | 0.487 |
| ISM_05565 | ISM_05560 | ISM_05565 | ISM_05560 | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | Glycosyl transferase, group 2 family protein; COG0463 Glycosyltransferases involved in cell wall biogenesis. | 0.691 |
| ISM_05565 | ISM_05570 | ISM_05565 | ISM_05570 | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.625 |
| ISM_05565 | ISM_14115 | ISM_05565 | ISM_14115 | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | ATP-dependent RNA helicase, DEAD/DEAH box family protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.487 |
| ISM_05565 | ISM_15460 | ISM_05565 | ISM_15460 | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. | 0.817 |
| ISM_05565 | ISM_15725 | ISM_05565 | ISM_15725 | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.621 |
| ISM_05565 | ISM_16445 | ISM_05565 | ISM_16445 | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | Iron-sulfur cluster assembly family protein; Belongs to the HesB/IscA family. | 0.821 |
| ISM_05565 | ISM_17200 | ISM_05565 | ISM_17200 | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.487 |
| ISM_05565 | cysQ | ISM_05565 | ISM_07035 | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.524 |
| ISM_05565 | frr | ISM_05565 | ISM_15015 | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.447 |
| ISM_05570 | ISM_05560 | ISM_05570 | ISM_05560 | Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Glycosyl transferase, group 2 family protein; COG0463 Glycosyltransferases involved in cell wall biogenesis. | 0.508 |
| ISM_05570 | ISM_05565 | ISM_05570 | ISM_05565 | Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | 0.625 |
| ISM_14115 | ISM_05565 | ISM_14115 | ISM_05565 | ATP-dependent RNA helicase, DEAD/DEAH box family protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | 0.487 |
| ISM_15460 | ISM_05565 | ISM_15460 | ISM_05565 | Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | 0.817 |
| ISM_15725 | ISM_05565 | ISM_15725 | ISM_05565 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | 0.621 |
| ISM_15725 | cysQ | ISM_15725 | ISM_07035 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.585 |
| ISM_16445 | ISM_05565 | ISM_16445 | ISM_05565 | Iron-sulfur cluster assembly family protein; Belongs to the HesB/IscA family. | COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. | 0.821 |