STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_05565COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family. (243 aa)    
Predicted Functional Partners:
ISM_15460
Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
 
 
 0.744
ISM_16445
Iron-sulfur cluster assembly family protein; Belongs to the HesB/IscA family.
 
 
 0.736
ISM_05560
Glycosyl transferase, group 2 family protein; COG0463 Glycosyltransferases involved in cell wall biogenesis.
       0.696
ISM_05570
Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
       0.625
ISM_15725
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
     
 0.562
ISM_17185
COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily.
  
   
 0.500
ISM_06115
NADH ubiquinone oxidoreductase, putative; COG0702 Predicted nucleoside-diphosphate-sugar epimerases.
  
 
 0.431
ISM_07725
COG0625 Glutathione S-transferase.
  
    0.431
ISM_06570
COG0500 SAM-dependent methyltransferases.
  
     0.411
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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