STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (557 aa)    
Predicted Functional Partners:
hutH
COG2986 Histidine ammonia-lyase.
 
 0.999
hutI
COG1228 Imidazolonepropionase and related amidohydrolases.
 
 
 0.999
ISM_14870
Amidohydrolase domain protein; COG0044 Dihydroorotase and related cyclic amidohydrolases.
  
 
 0.895
ISM_02740
Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.
 
  
 0.795
ISM_02745
Histidine utilization repressor; COG2188 Transcriptional regulators.
 
  
 0.782
ISM_07160
COG3741 N-formylglutamate amidohydrolase.
  
  
 0.512
ISM_04990
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
     
 0.501
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
    0.489
ISM_05645
Hypothetical protein; COG3443 Predicted periplasmic or secreted protein.
       0.436
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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