STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutHCOG2986 Histidine ammonia-lyase. (512 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.999
hutI
COG1228 Imidazolonepropionase and related amidohydrolases.
 
  
 0.995
hisD-2
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.919
ISM_14870
Amidohydrolase domain protein; COG0044 Dihydroorotase and related cyclic amidohydrolases.
  
  
 0.846
ISM_02740
Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.
 
  
 0.802
ISM_02745
Histidine utilization repressor; COG2188 Transcriptional regulators.
 
  
 0.800
ISM_08755
COG1448 Aspartate/tyrosine/aromatic aminotransferase.
   
 
  0.778
ISM_02505
COG0287 Prephenate dehydrogenase.
     
 0.755
hisC
COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
    
 0.664
ISM_04690
COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.
    
 0.664
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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