| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_02340 | ISM_14535 | ISM_02340 | ISM_14535 | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | 0.423 |
| ISM_02340 | ISM_14665 | ISM_02340 | ISM_14665 | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | 0.575 |
| ISM_02340 | ISM_15215 | ISM_02340 | ISM_15215 | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | Agmatinase, putative; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | 0.607 |
| ISM_02340 | hutH | ISM_02340 | ISM_05635 | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | COG2986 Histidine ammonia-lyase. | 0.553 |
| ISM_02340 | hutI | ISM_02340 | ISM_05640 | Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family. | COG1228 Imidazolonepropionase and related amidohydrolases. | 0.566 |
| ISM_02740 | ISM_02745 | ISM_02740 | ISM_02745 | Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | Histidine utilization repressor; COG2188 Transcriptional regulators. | 0.802 |
| ISM_02740 | ISM_07160 | ISM_02740 | ISM_07160 | Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG3741 N-formylglutamate amidohydrolase. | 0.788 |
| ISM_02740 | hutH | ISM_02740 | ISM_05635 | Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG2986 Histidine ammonia-lyase. | 0.802 |
| ISM_02740 | hutI | ISM_02740 | ISM_05640 | Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG1228 Imidazolonepropionase and related amidohydrolases. | 0.989 |
| ISM_02740 | hutU | ISM_02740 | ISM_05630 | Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. | 0.795 |
| ISM_02745 | ISM_02740 | ISM_02745 | ISM_02740 | Histidine utilization repressor; COG2188 Transcriptional regulators. | Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | 0.802 |
| ISM_02745 | ISM_07160 | ISM_02745 | ISM_07160 | Histidine utilization repressor; COG2188 Transcriptional regulators. | COG3741 N-formylglutamate amidohydrolase. | 0.523 |
| ISM_02745 | hutH | ISM_02745 | ISM_05635 | Histidine utilization repressor; COG2188 Transcriptional regulators. | COG2986 Histidine ammonia-lyase. | 0.800 |
| ISM_02745 | hutI | ISM_02745 | ISM_05640 | Histidine utilization repressor; COG2188 Transcriptional regulators. | COG1228 Imidazolonepropionase and related amidohydrolases. | 0.879 |
| ISM_02745 | hutU | ISM_02745 | ISM_05630 | Histidine utilization repressor; COG2188 Transcriptional regulators. | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. | 0.782 |
| ISM_04465 | ISM_07160 | ISM_04465 | ISM_07160 | Probable guanine deaminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG3741 N-formylglutamate amidohydrolase. | 0.541 |
| ISM_04465 | hutI | ISM_04465 | ISM_05640 | Probable guanine deaminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG1228 Imidazolonepropionase and related amidohydrolases. | 0.704 |
| ISM_07160 | ISM_02740 | ISM_07160 | ISM_02740 | COG3741 N-formylglutamate amidohydrolase. | Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | 0.788 |
| ISM_07160 | ISM_02745 | ISM_07160 | ISM_02745 | COG3741 N-formylglutamate amidohydrolase. | Histidine utilization repressor; COG2188 Transcriptional regulators. | 0.523 |
| ISM_07160 | ISM_04465 | ISM_07160 | ISM_04465 | COG3741 N-formylglutamate amidohydrolase. | Probable guanine deaminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | 0.541 |