Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ISM_06090Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (241 aa)    
Predicted Functional Partners:
ISM_06085
Helicase, ATP-dependent, putative; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.
       0.789
ISM_16740
Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins.
  
 
 0.712
ISM_07955
7-alpha-hydroxysteroid dehydrogenase, putative; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 
  0.597
ISM_10366
Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 
  0.589
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
       0.535
ISM_15920
Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 
  0.527
ISM_16730
Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase.
    
 0.509
ISM_09361
Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.
      0.489
ISM_09496
acetoacetyl-CoA reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 
  0.484
ISM_11785
L-threonine aldolase, low-specificity, putative; COG2008 Threonine aldolase.
    
 0.468
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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