Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_06100Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. (1508 aa)    
Predicted Functional Partners:
ISM_06020
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 0.999
ISM_06105
COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
 0.999
ISM_12240
Hypothetical protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 0.999
ISM_12680
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 0.999
ISM_13640
Pyridine nucleotide-disulphide oxidoreductase family protein; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
 0.999
ISM_12965
COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.978
ISM_13930
Glutamate/leucine/phenylalanine/valine dehydrogenase family protein; COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.967
ISM_04900
Iron-sulfur cluster-binding protein; COG1145 Ferredoxin.
   
  0.956
carB
COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
  
 
 0.954
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.953
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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