STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_06255Alkylphosphonate utilization protein PhnH; COG3625 Uncharacterized enzyme of phosphonate metabolism. (191 aa)    
Predicted Functional Partners:
ISM_06235
Alkylphosphonate utilization protein PhnL; COG4778 ABC-type phosphonate transport system, ATPase component.
 
 0.999
ISM_06240
Alkylphosphonate utilization protein PhnK; COG4107 ABC-type phosphonate transport system, ATPase component.
 
 
 0.999
ISM_06245
Alkylphosphonate utilization protein PhnJ; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family.
 
 
 0.999
ISM_06250
Alkylphosphonate utilization protein PhnI; COG3626 Uncharacterized enzyme of phosphonate metabolism.
 
 0.999
ISM_06260
Alkylphosphonate utilization protein PhnG; COG3624 Uncharacterized enzyme of phosphonate metabolism.
 
 0.999
ISM_06225
Alkylphosphonate utilization protein PhnM; COG3454 Metal-dependent hydrolase involved in phosphonate metabolism.
 
 
 0.993
ISM_11880
Alkylphosphonate utilization protein PhnM, putative; COG3454 Metal-dependent hydrolase involved in phosphonate metabolism.
 
 
 0.982
phnN
Hypothetical protein; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
 
  
 0.977
ISM_06265
Transcriptional regulator, GntR family protein; COG2188 Transcriptional regulators.
 
  
 0.977
phnC
Phosphonate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
 
  
 0.958
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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