STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_06330COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. (490 aa)    
Predicted Functional Partners:
ISM_06325
Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
     0.810
ISM_13450
Corrinoid methyltransferase protein, putative; COG5012 Predicted cobalamin binding protein.
 
  
  0.809
ISM_06320
Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
     0.800
ISM_16340
COG3894 Uncharacterized metal-binding protein.
 
     0.774
ISM_13445
Hypothetical protein.
 
     0.761
ISM_15125
Hypothetical protein.
 
     0.761
ISM_15115
Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain.
 
     0.725
ISM_06335
Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators.
 
     0.611
ISM_13465
Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
  
     0.602
ISM_17065
Oxidoreductase, NAD-binding site; COG0665 Glycine/D-amino acid oxidases (deaminating).
  
     0.567
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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