| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_06320 | ISM_06325 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.800 |
| ISM_06320 | ISM_06330 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.799 |
| ISM_06320 | ISM_06335 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.597 |
| ISM_06325 | ISM_06320 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.800 |
| ISM_06325 | ISM_06330 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.809 |
| ISM_06325 | ISM_06335 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.605 |
| ISM_06330 | ISM_06320 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.799 |
| ISM_06330 | ISM_06325 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.809 |
| ISM_06330 | ISM_06335 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.611 |
| ISM_06330 | ISM_08155 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Flavin-containing monooxygenase; COG2072 Predicted flavoprotein involved in K+ transport. | 0.595 |
| ISM_06330 | ISM_13445 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Hypothetical protein. | 0.763 |
| ISM_06330 | ISM_13450 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Corrinoid methyltransferase protein, putative; COG5012 Predicted cobalamin binding protein. | 0.909 |
| ISM_06330 | ISM_13465 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.602 |
| ISM_06330 | ISM_15115 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | 0.727 |
| ISM_06330 | ISM_15125 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Hypothetical protein. | 0.763 |
| ISM_06330 | ISM_16340 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | COG3894 Uncharacterized metal-binding protein. | 0.775 |
| ISM_06335 | ISM_06320 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.597 |
| ISM_06335 | ISM_06325 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.605 |
| ISM_06335 | ISM_06330 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.611 |
| ISM_08155 | ISM_06330 | Flavin-containing monooxygenase; COG2072 Predicted flavoprotein involved in K+ transport. | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.595 |