| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_03340 | ISM_06335 | ISM_03340 | ISM_06335 | COG1802 Transcriptional regulators. | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.755 |
| ISM_03340 | ISM_13645 | ISM_03340 | ISM_13645 | COG1802 Transcriptional regulators. | Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators. | 0.591 |
| ISM_03340 | prmC | ISM_03340 | ISM_14685 | COG1802 Transcriptional regulators. | Modification methylase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.551 |
| ISM_06320 | ISM_06325 | ISM_06320 | ISM_06325 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.801 |
| ISM_06320 | ISM_06330 | ISM_06320 | ISM_06330 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.800 |
| ISM_06320 | ISM_06335 | ISM_06320 | ISM_06335 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.597 |
| ISM_06320 | ISM_06345 | ISM_06320 | ISM_06345 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family. | 0.437 |
| ISM_06325 | ISM_06320 | ISM_06325 | ISM_06320 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.801 |
| ISM_06325 | ISM_06330 | ISM_06325 | ISM_06330 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.810 |
| ISM_06325 | ISM_06335 | ISM_06325 | ISM_06335 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.605 |
| ISM_06325 | ISM_06345 | ISM_06325 | ISM_06345 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family. | 0.437 |
| ISM_06330 | ISM_06320 | ISM_06330 | ISM_06320 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.800 |
| ISM_06330 | ISM_06325 | ISM_06330 | ISM_06325 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.810 |
| ISM_06330 | ISM_06335 | ISM_06330 | ISM_06335 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.611 |
| ISM_06335 | ISM_03340 | ISM_06335 | ISM_03340 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | COG1802 Transcriptional regulators. | 0.755 |
| ISM_06335 | ISM_06320 | ISM_06335 | ISM_06320 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.597 |
| ISM_06335 | ISM_06325 | ISM_06335 | ISM_06325 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.605 |
| ISM_06335 | ISM_06330 | ISM_06335 | ISM_06330 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.611 |
| ISM_06335 | ISM_06340 | ISM_06335 | ISM_06340 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | Trk system potassium uptake protein TrkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. | 0.508 |
| ISM_06335 | ISM_06345 | ISM_06335 | ISM_06345 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family. | 0.508 |