| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_06430 | ISM_16730 | ISM_06430 | ISM_16730 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | 0.972 |
| ISM_06430 | fmt | ISM_06430 | ISM_13735 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.969 |
| ISM_06430 | nusA | ISM_06430 | ISM_06530 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. | 0.963 |
| ISM_06430 | rlmE | ISM_06430 | ISM_15135 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.954 |
| ISM_06430 | rlmN | ISM_06430 | ISM_10665 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Radical SAM enzyme, Cfr family protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.945 |
| ISM_06430 | rpmD | ISM_06430 | ISM_01710 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | COG1841 Ribosomal protein L30/L7E. | 0.945 |
| ISM_06430 | rpoB | ISM_06430 | ISM_01895 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.968 |
| ISM_06430 | rpoC | ISM_06430 | ISM_01890 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.991 |
| ISM_06430 | rpsJ | ISM_06430 | ISM_01845 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.978 |
| ISM_06430 | truB | ISM_06430 | ISM_06405 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.943 |
| ISM_16730 | ISM_06430 | ISM_16730 | ISM_06430 | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.972 |
| ISM_16730 | fmt | ISM_16730 | ISM_13735 | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.777 |
| ISM_16730 | rlmN | ISM_16730 | ISM_10665 | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | Radical SAM enzyme, Cfr family protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.574 |
| ISM_16730 | rpoB | ISM_16730 | ISM_01895 | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.454 |
| ISM_16730 | rpoC | ISM_16730 | ISM_01890 | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.712 |
| fmt | ISM_06430 | ISM_13735 | ISM_06430 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.969 |
| fmt | ISM_16730 | ISM_13735 | ISM_16730 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | 0.777 |
| fmt | rlmN | ISM_13735 | ISM_10665 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Radical SAM enzyme, Cfr family protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.509 |
| fmt | rpoC | ISM_13735 | ISM_01890 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.577 |
| nusA | ISM_06430 | ISM_06530 | ISM_06430 | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.963 |