Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
ISM_06565Competence protein F, putative; COG1040 Predicted amidophosphoribosyltransferases. (195 aa)    
Predicted Functional Partners:
ISM_03140
DNA processing protein DprA, putative; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.
 
 
 0.904
ISM_06560
Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
 
     0.802
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.791
ISM_06550
Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators.
  
    0.791
ISM_02505
COG0287 Prephenate dehydrogenase.
   
    0.786
ISM_10021
Competence protein ComM; COG0606 Predicted ATPase with chaperone activity.
 
  
 0.773
ISM_06480
COG2003 DNA repair proteins; Belongs to the UPF0758 family.
 
    0.767
ISM_14760
Competence protein; COG0658 Predicted membrane metal-binding protein.
 
  
 0.740
ISM_06555
Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase.
     
 0.717
xerC-2
Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
  
    0.690
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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