| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_02505 | ISM_06565 | ISM_02505 | ISM_06565 | COG0287 Prephenate dehydrogenase. | Competence protein F, putative; COG1040 Predicted amidophosphoribosyltransferases. | 0.762 |
| ISM_02505 | apt | ISM_02505 | ISM_01435 | COG0287 Prephenate dehydrogenase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.750 |
| ISM_03140 | ISM_06480 | ISM_03140 | ISM_06480 | DNA processing protein DprA, putative; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | COG2003 DNA repair proteins; Belongs to the UPF0758 family. | 0.723 |
| ISM_03140 | ISM_06565 | ISM_03140 | ISM_06565 | DNA processing protein DprA, putative; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | Competence protein F, putative; COG1040 Predicted amidophosphoribosyltransferases. | 0.931 |
| ISM_03140 | ISM_10021 | ISM_03140 | ISM_10021 | DNA processing protein DprA, putative; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | Competence protein ComM; COG0606 Predicted ATPase with chaperone activity. | 0.809 |
| ISM_03140 | ISM_13150 | ISM_03140 | ISM_13150 | DNA processing protein DprA, putative; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. | 0.781 |
| ISM_03140 | ISM_14760 | ISM_03140 | ISM_14760 | DNA processing protein DprA, putative; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | Competence protein; COG0658 Predicted membrane metal-binding protein. | 0.822 |
| ISM_06480 | ISM_03140 | ISM_06480 | ISM_03140 | COG2003 DNA repair proteins; Belongs to the UPF0758 family. | DNA processing protein DprA, putative; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | 0.723 |
| ISM_06480 | ISM_06565 | ISM_06480 | ISM_06565 | COG2003 DNA repair proteins; Belongs to the UPF0758 family. | Competence protein F, putative; COG1040 Predicted amidophosphoribosyltransferases. | 0.961 |
| ISM_06480 | ISM_10021 | ISM_06480 | ISM_10021 | COG2003 DNA repair proteins; Belongs to the UPF0758 family. | Competence protein ComM; COG0606 Predicted ATPase with chaperone activity. | 0.527 |
| ISM_06480 | ISM_14760 | ISM_06480 | ISM_14760 | COG2003 DNA repair proteins; Belongs to the UPF0758 family. | Competence protein; COG0658 Predicted membrane metal-binding protein. | 0.634 |
| ISM_06550 | ISM_06555 | ISM_06550 | ISM_06555 | Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | 0.810 |
| ISM_06550 | ISM_06560 | ISM_06550 | ISM_06560 | Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. | Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.858 |
| ISM_06550 | ISM_06565 | ISM_06550 | ISM_06565 | Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. | Competence protein F, putative; COG1040 Predicted amidophosphoribosyltransferases. | 0.804 |
| ISM_06555 | ISM_06550 | ISM_06555 | ISM_06550 | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. | 0.810 |
| ISM_06555 | ISM_06560 | ISM_06555 | ISM_06560 | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.848 |
| ISM_06555 | ISM_06565 | ISM_06555 | ISM_06565 | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | Competence protein F, putative; COG1040 Predicted amidophosphoribosyltransferases. | 0.726 |
| ISM_06560 | ISM_06550 | ISM_06560 | ISM_06550 | Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators. | 0.858 |
| ISM_06560 | ISM_06555 | ISM_06560 | ISM_06555 | Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Hydrolase, carbon-nitrogen family protein; COG0388 Predicted amidohydrolase. | 0.848 |
| ISM_06560 | ISM_06565 | ISM_06560 | ISM_06565 | Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Competence protein F, putative; COG1040 Predicted amidophosphoribosyltransferases. | 0.813 |