STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
rbsKPutative RbsK, Carbohydrate kinase, ribokinase family protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (286 aa)    
Predicted Functional Partners:
prs
Phosphoribosyl pyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.965
ISM_13350
COG0021 Transketolase; Belongs to the transketolase family.
  
 0.940
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.927
ISM_02820
Phosphomannomutase/phosphoglucomutase; COG1109 Phosphomannomutase.
   
 
 0.916
ISM_15450
COG1957 Inosine-uridine nucleoside N-ribohydrolase.
 
 
 0.902
ISM_06675
Phosphate acetyltransferase; COG0281 Malic enzyme.
  
  
 0.835
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.824
ISM_13845
COG0698 Ribose 5-phosphate isomerase RpiB.
  
 
 0.817
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.795
ISM_06310
COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.787
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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