| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_00075 | dnaJ | ISM_00075 | ISM_08460 | Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific; Belongs to the pseudouridine synthase RluA family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.643 |
| ISM_00075 | mnmE | ISM_00075 | ISM_06735 | Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific; Belongs to the pseudouridine synthase RluA family. | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.869 |
| ISM_00075 | mnmG | ISM_00075 | ISM_06730 | Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific; Belongs to the pseudouridine synthase RluA family. | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.624 |
| ISM_06715 | ISM_06720 | ISM_06715 | ISM_06720 | Chromosome partitioning protein parB; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | COG1192 ATPases involved in chromosome partitioning. | 0.989 |
| ISM_06715 | mnmE | ISM_06715 | ISM_06735 | Chromosome partitioning protein parB; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.891 |
| ISM_06715 | mnmG | ISM_06715 | ISM_06730 | Chromosome partitioning protein parB; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.836 |
| ISM_06715 | rho | ISM_06715 | ISM_06740 | Chromosome partitioning protein parB; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.641 |
| ISM_06715 | rsmG | ISM_06715 | ISM_06725 | Chromosome partitioning protein parB; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | Glucose-inhibited division protein B; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.929 |
| ISM_06720 | ISM_06715 | ISM_06720 | ISM_06715 | COG1192 ATPases involved in chromosome partitioning. | Chromosome partitioning protein parB; COG1475 Predicted transcriptional regulators; Belongs to the ParB family. | 0.989 |
| ISM_06720 | mnmE | ISM_06720 | ISM_06735 | COG1192 ATPases involved in chromosome partitioning. | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.836 |
| ISM_06720 | mnmG | ISM_06720 | ISM_06730 | COG1192 ATPases involved in chromosome partitioning. | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.845 |
| ISM_06720 | rho | ISM_06720 | ISM_06740 | COG1192 ATPases involved in chromosome partitioning. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.645 |
| ISM_06720 | rsmG | ISM_06720 | ISM_06725 | COG1192 ATPases involved in chromosome partitioning. | Glucose-inhibited division protein B; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.899 |
| ISM_13970 | mnmG | ISM_13970 | ISM_06730 | Hypothetical protein. | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.719 |
| ISM_15465 | mnmG | ISM_15465 | ISM_06730 | Hypothetical protein. | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.701 |
| dnaJ | ISM_00075 | ISM_08460 | ISM_00075 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific; Belongs to the pseudouridine synthase RluA family. | 0.643 |
| dnaJ | mnmE | ISM_08460 | ISM_06735 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.775 |
| dnaJ | mnmG | ISM_08460 | ISM_06730 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.606 |
| dnaJ | yidC | ISM_08460 | ISM_05275 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Inner membrane protein YidC, putative; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.472 |
| mnmE | ISM_00075 | ISM_06735 | ISM_00075 | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Ribosomal large subunit pseudouridine synthase D; COG0564 Pseudouridylate synthases, 23S RNA-specific; Belongs to the pseudouridine synthase RluA family. | 0.869 |
