| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_04010 | ISM_06800 | ISM_04010 | ISM_06800 | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | COG0477 Permeases of the major facilitator superfamily. | 0.495 |
| ISM_04010 | ISM_16740 | ISM_04010 | ISM_16740 | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.512 |
| ISM_05125 | ISM_06800 | ISM_05125 | ISM_06800 | Ferric iron ABC transporter, periplasmic ferric iron-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component. | COG0477 Permeases of the major facilitator superfamily. | 0.733 |
| ISM_05365 | ISM_06180 | ISM_05365 | ISM_06180 | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | 0.958 |
| ISM_05365 | ISM_06800 | ISM_05365 | ISM_06800 | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | COG0477 Permeases of the major facilitator superfamily. | 0.440 |
| ISM_05365 | ISM_16740 | ISM_05365 | ISM_16740 | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.509 |
| ISM_06180 | ISM_05365 | ISM_06180 | ISM_05365 | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | 0.958 |
| ISM_06180 | ISM_06800 | ISM_06180 | ISM_06800 | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | COG0477 Permeases of the major facilitator superfamily. | 0.487 |
| ISM_06800 | ISM_04010 | ISM_06800 | ISM_04010 | COG0477 Permeases of the major facilitator superfamily. | Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases. | 0.495 |
| ISM_06800 | ISM_05125 | ISM_06800 | ISM_05125 | COG0477 Permeases of the major facilitator superfamily. | Ferric iron ABC transporter, periplasmic ferric iron-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component. | 0.733 |
| ISM_06800 | ISM_05365 | ISM_06800 | ISM_05365 | COG0477 Permeases of the major facilitator superfamily. | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | 0.440 |
| ISM_06800 | ISM_06180 | ISM_06800 | ISM_06180 | COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. | 0.487 |
| ISM_06800 | ISM_09040 | ISM_06800 | ISM_09040 | COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein. | 0.465 |
| ISM_06800 | ISM_09411 | ISM_06800 | ISM_09411 | COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein. | 0.540 |
| ISM_06800 | ISM_16740 | ISM_06800 | ISM_16740 | COG0477 Permeases of the major facilitator superfamily. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.545 |
| ISM_06800 | dddP | ISM_06800 | ISM_05385 | COG0477 Permeases of the major facilitator superfamily. | Metallopeptidase, family M24; Able to cleave dimethlysulfonioproprionate (DMSP), releasing dimethyl sulfide (DMS). DMS is the principal form by which sulfur is transported from oceans to the atmosphere. The real activity of the protein is however subject to debate and it is unclear whether it constitutes a real dimethlysulfonioproprionate lyase in vivo: the low activity with DMSP as substrate suggests that DMSP is not its native substrate. | 0.518 |
| ISM_06800 | hslU | ISM_06800 | ISM_06805 | COG0477 Permeases of the major facilitator superfamily. | ATP-dependent protease ATP-binding subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.536 |
| ISM_06800 | polA | ISM_06800 | ISM_09075 | COG0477 Permeases of the major facilitator superfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.526 |
| ISM_09040 | ISM_06800 | ISM_09040 | ISM_06800 | Hypothetical protein. | COG0477 Permeases of the major facilitator superfamily. | 0.465 |
| ISM_09411 | ISM_06800 | ISM_09411 | ISM_06800 | Hypothetical protein. | COG0477 Permeases of the major facilitator superfamily. | 0.540 |
