Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_06845Hypothetical protein; COG2202 FOG: PAS/PAC domain. (499 aa)    
Predicted Functional Partners:
ISM_06825
Hypothetical protein; COG3893 Inactivated superfamily I helicase.
 
     0.872
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 
 0.829
ISM_15565
Hypothetical protein.
  
    0.822
ISM_09906
Glycosyl transferase, group 2 family protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.
  
  
 0.813
ISM_06850
COG0642 Signal transduction histidine kinase.
   
 0.779
ISM_01200
COG1868 Flagellar motor switch protein.
 
 
 0.748
ISM_16640
Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific.
  
 0.742
ISM_06830
Nucleotidyltransferase family protein; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).
     
 0.722
ISM_06820
ATP-dependent DNA helicase, UvrD/Rep family protein; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); Belongs to the helicase family. UvrD subfamily.
       0.720
ISM_06835
Hypothetical protein; COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases.
       0.720
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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