Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_06995PTS IIA-like nitrogen-regulatory protein PtsN; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). (154 aa)    
Predicted Functional Partners:
hpf
Ribosomal subunit interface protein, putative; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
  
  
 0.929
ISM_13565
Phosphocarrier protein HPr; COG1925 Phosphotransferase system, HPr-related proteins.
 
 
 0.915
ISM_13560
PTS system IIA component, Man family protein; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA.
 
 
 0.880
ISM_13555
Hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.834
ISM_01385
Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family.
  
   
 0.803
ISM_13550
Putative kinase/phosphatase; COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism.
 
   
 0.665
ISM_14135
Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.639
ISM_06980
COG1934 Uncharacterized protein conserved in bacteria.
  
  
 0.620
ISM_06985
ABC transporter, ATP-binding protein; COG1137 ABC-type (unclassified) transport system, ATPase component.
  
  
 0.602
ISM_01205
Sensor histidine kinase; COG0591 Na+/proline symporter.
  
 
 0.514
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.