| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_01365 | ISM_07160 | ISM_01365 | ISM_07160 | COG5319 Uncharacterized protein conserved in bacteria. | COG3741 N-formylglutamate amidohydrolase. | 0.536 |
| ISM_02740 | ISM_07160 | ISM_02740 | ISM_07160 | Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG3741 N-formylglutamate amidohydrolase. | 0.777 |
| ISM_02740 | hutI | ISM_02740 | ISM_05640 | Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG1228 Imidazolonepropionase and related amidohydrolases. | 0.981 |
| ISM_06040 | ISM_06100 | ISM_06040 | ISM_06100 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.734 |
| ISM_06040 | ISM_06675 | ISM_06040 | ISM_06675 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.908 |
| ISM_06040 | ISM_07160 | ISM_06040 | ISM_07160 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | COG3741 N-formylglutamate amidohydrolase. | 0.640 |
| ISM_06040 | ISM_09586 | ISM_06040 | ISM_09586 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Malate dehydrogenase; COG0281 Malic enzyme. | 0.908 |
| ISM_06100 | ISM_06040 | ISM_06100 | ISM_06040 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.734 |
| ISM_06100 | ISM_06675 | ISM_06100 | ISM_06675 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.502 |
| ISM_06100 | ISM_07160 | ISM_06100 | ISM_07160 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG3741 N-formylglutamate amidohydrolase. | 0.868 |
| ISM_06100 | ISM_08325 | ISM_06100 | ISM_08325 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.920 |
| ISM_06100 | ISM_09586 | ISM_06100 | ISM_09586 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Malate dehydrogenase; COG0281 Malic enzyme. | 0.502 |
| ISM_06675 | ISM_06040 | ISM_06675 | ISM_06040 | Phosphate acetyltransferase; COG0281 Malic enzyme. | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.908 |
| ISM_06675 | ISM_06100 | ISM_06675 | ISM_06100 | Phosphate acetyltransferase; COG0281 Malic enzyme. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.502 |
| ISM_06675 | ISM_07160 | ISM_06675 | ISM_07160 | Phosphate acetyltransferase; COG0281 Malic enzyme. | COG3741 N-formylglutamate amidohydrolase. | 0.636 |
| ISM_06675 | ISM_09586 | ISM_06675 | ISM_09586 | Phosphate acetyltransferase; COG0281 Malic enzyme. | Malate dehydrogenase; COG0281 Malic enzyme. | 0.786 |
| ISM_07160 | ISM_01365 | ISM_07160 | ISM_01365 | COG3741 N-formylglutamate amidohydrolase. | COG5319 Uncharacterized protein conserved in bacteria. | 0.536 |
| ISM_07160 | ISM_02740 | ISM_07160 | ISM_02740 | COG3741 N-formylglutamate amidohydrolase. | Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | 0.777 |
| ISM_07160 | ISM_06040 | ISM_07160 | ISM_06040 | COG3741 N-formylglutamate amidohydrolase. | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.640 |
| ISM_07160 | ISM_06100 | ISM_07160 | ISM_06100 | COG3741 N-formylglutamate amidohydrolase. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.868 |