Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_07305COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family. (368 aa)    
Predicted Functional Partners:
ISM_15625
COG1960 Acyl-CoA dehydrogenases.
 
 0.799
ISM_07300
Thiol:disulfide interchange protein, DsbA family protein; COG1651 Protein-disulfide isomerase.
       0.790
ISM_07295
Hypothetical protein; COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives.
       0.747
ISM_09941
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
    
 0.713
ISM_16800
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
    
 0.713
ISM_06675
Phosphate acetyltransferase; COG0281 Malic enzyme.
     
 0.684
ISM_09586
Malate dehydrogenase; COG0281 Malic enzyme.
     
 0.684
ISM_05030
Hypothetical protein; COG2030 Acyl dehydratase.
  
 
 0.679
ISM_14700
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
 
  
 0.663
ISM_16910
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
  0.627
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (18%) [HD]