Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_07310NifS-related protein; COG0520 Selenocysteine lyase. (417 aa)    
Predicted Functional Partners:
ISM_15105
Hypothetical protein; COG0822 NifU homolog involved in Fe-S cluster formation.
  
 0.964
ISM_15975
FeS assembly ATPase SufC; COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.
 
  
 0.860
ISM_13420
Fe-S metabolism associated family protein; COG2166 SufE protein probably involved in Fe-S center assembly.
  
 0.848
ISM_15970
FeS assembly protein SufD; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
 
 
 0.779
ISM_16005
FeS assembly protein SufB; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
 
 
 0.778
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.690
ISM_14135
Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.652
ISM_00810
Possible endonuclease/exonuclease/phosphatase family protein.
    
   0.619
ISM_07785
Hypothetical protein; COG3568 Metal-dependent hydrolase.
    
   0.619
ISM_07945
Hypothetical protein.
    
   0.619
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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