STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_07360COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases. (264 aa)    
Predicted Functional Partners:
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
  
 
 0.801
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
  
 
 0.611
ISM_07365
Nidogen, extracellular region; COG2931 RTX toxins and related Ca2+-binding proteins.
    
  0.602
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
   
 
 0.591
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.577
ISM_04775
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
     
 0.566
ISM_05545
Histidine kinase/response regulator hybrid protein; COG2202 FOG: PAS/PAC domain.
     
 0.566
ISM_12905
Multi-sensor Signal Transduction Histidine Kinase; COG2202 FOG: PAS/PAC domain.
    
 0.515
ISM_08860
Adenylate/guanylate cyclase/hydrolase, alpha/beta fold family protein; COG3710 DNA-binding winged-HTH domains.
     
 0.499
leuS
COG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.489
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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