| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_06020 | ISM_06100 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.999 |
| ISM_06020 | ISM_07475 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family. | 0.920 |
| ISM_06020 | ISM_12240 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Hypothetical protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.589 |
| ISM_06020 | ISM_12680 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.592 |
| ISM_06020 | ISM_12965 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.726 |
| ISM_06020 | ISM_13930 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Glutamate/leucine/phenylalanine/valine dehydrogenase family protein; COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.726 |
| ISM_06020 | ISM_15335 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Glutamine amidotransferase-like protein; COG0067 Glutamate synthase domain 1. | 0.928 |
| ISM_06020 | ISM_16945 | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Glutamine amidotransferase, class II; COG0067 Glutamate synthase domain 1. | 0.928 |
| ISM_06100 | ISM_06020 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.999 |
| ISM_06100 | ISM_06105 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.999 |
| ISM_06100 | ISM_07475 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family. | 0.978 |
| ISM_06100 | ISM_12240 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Hypothetical protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.999 |
| ISM_06100 | ISM_12680 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.999 |
| ISM_06100 | ISM_12965 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.999 |
| ISM_06100 | ISM_13640 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.999 |
| ISM_06100 | ISM_13930 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Glutamate/leucine/phenylalanine/valine dehydrogenase family protein; COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.999 |
| ISM_06100 | ISM_15335 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Glutamine amidotransferase-like protein; COG0067 Glutamate synthase domain 1. | 0.979 |
| ISM_06100 | ISM_16945 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Glutamine amidotransferase, class II; COG0067 Glutamate synthase domain 1. | 0.979 |
| ISM_06105 | ISM_06100 | COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.999 |
| ISM_06105 | ISM_07475 | COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family. | 0.986 |