| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_05070 | ISM_06100 | ISM_05070 | ISM_06100 | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.906 |
| ISM_05070 | ISM_07495 | ISM_05070 | ISM_07495 | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.655 |
| ISM_05070 | ISM_08325 | ISM_05070 | ISM_08325 | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.422 |
| ISM_05070 | ISM_08755 | ISM_05070 | ISM_08755 | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 0.821 |
| ISM_05070 | ISM_14750 | ISM_05070 | ISM_14750 | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.924 |
| ISM_05070 | ISM_16740 | ISM_05070 | ISM_16740 | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.429 |
| ISM_05070 | pckA | ISM_05070 | ISM_13535 | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.624 |
| ISM_05875 | ISM_07495 | ISM_05875 | ISM_07495 | phenylacetate-CoA ligase, putative; COG1541 Coenzyme F390 synthetase. | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.758 |
| ISM_05875 | ISM_16740 | ISM_05875 | ISM_16740 | phenylacetate-CoA ligase, putative; COG1541 Coenzyme F390 synthetase. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.552 |
| ISM_06100 | ISM_05070 | ISM_06100 | ISM_05070 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.906 |
| ISM_06100 | ISM_07495 | ISM_06100 | ISM_07495 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.675 |
| ISM_06100 | ISM_08325 | ISM_06100 | ISM_08325 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.932 |
| ISM_06100 | ISM_08755 | ISM_06100 | ISM_08755 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 0.922 |
| ISM_06100 | ISM_14750 | ISM_06100 | ISM_14750 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.927 |
| ISM_06100 | ISM_16740 | ISM_06100 | ISM_16740 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.942 |
| ISM_06100 | pckA | ISM_06100 | ISM_13535 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.891 |
| ISM_07490 | ISM_07495 | ISM_07490 | ISM_07495 | Hypothetical protein; COG0684 Demethylmenaquinone methyltransferase. | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.854 |
| ISM_07495 | ISM_05070 | ISM_07495 | ISM_05070 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.655 |
| ISM_07495 | ISM_05875 | ISM_07495 | ISM_05875 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | phenylacetate-CoA ligase, putative; COG1541 Coenzyme F390 synthetase. | 0.758 |
| ISM_07495 | ISM_06100 | ISM_07495 | ISM_06100 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.675 |