STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_07660TIR. (296 aa)    
Predicted Functional Partners:
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolaseII, putative; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
 
 0.831
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
   
 0.763
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
    
 0.760
ISM_04775
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
    
 0.725
ISM_05545
Histidine kinase/response regulator hybrid protein; COG2202 FOG: PAS/PAC domain.
    
 0.725
ISM_01565
Response regulator receiver protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.
   
 0.697
ISM_17795
Y4BN.
   
 
 0.688
ISM_14885
Xanthine dehydrogenase family protein, small/large subunits; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.
     
  0.630
ISM_10161
Anti-sigma B factor, putative; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase).
    
 
 0.602
ISM_07425
Putative two-component system sensor histidine kinase; COG2203 FOG: GAF domain.
   
 
 0.584
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.