STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_07660TIR. (296 aa)    
Predicted Functional Partners:
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
    
 0.839
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolaseII, putative; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
 
 0.804
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
    
 0.777
ISM_01565
Response regulator receiver protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.
   
 0.772
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
    
 0.738
ISM_10161
Anti-sigma B factor, putative; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase).
    
 
 0.668
ISM_04775
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
    
 0.613
ISM_05545
Histidine kinase/response regulator hybrid protein; COG2202 FOG: PAS/PAC domain.
    
 0.613
ISM_07410
COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis.
  
 
 
 0.611
ISM_14510
Sigma-24 (FecI); COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 
 0.578
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.