STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_07810Hydantoinase/oxoprolinase family protein; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. (666 aa)    
Predicted Functional Partners:
ISM_14425
COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit.
 0.989
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
    
 0.781
ISM_08325
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
    
  0.686
queG
Iron-sulfur cluster-binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.
       0.671
ISM_04640
COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family.
  
     0.568
ISM_07820
COG0031 Cysteine synthase.
  
    0.533
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
       0.529
ISM_07825
Oxidoreductase, FMN-binding/pyridine nucleotide-disulfideoxidoreductase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
    0.506
ISM_03665
COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family.
  
     0.490
ISM_04415
DNA-binding protein, putative; COG1396 Predicted transcriptional regulators.
 
    0.449
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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