STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_07880Hypothetical protein; COG0006 Xaa-Pro aminopeptidase. (393 aa)    
Predicted Functional Partners:
ectC
Ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.
  
  
  0.932
ISM_04200
Putative L-proline 4-hydroxylase.
  
  
 0.676
ISM_12525
Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
     0.641
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.634
potA-6
Polyamine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
 
     0.587
ISM_13925
Succinylglutamate desuccinylase/aspartoacylase; COG3608 Predicted deacylase.
 
  
 0.585
ISM_09346
Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
 
 0.582
ISM_07890
Polyamine ABC trasnporter, periplasmic polyamine-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.
 
    0.570
ISM_09341
COG4311 Sarcosine oxidase delta subunit.
  
  
  0.568
ISM_09351
COG4583 Sarcosine oxidase gamma subunit.
  
  
  0.560
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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