Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_07920COG1846 Transcriptional regulators. (165 aa)    
Predicted Functional Partners:
ISM_07925
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
     
 0.784
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
       0.581
ISM_10006
Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.
  
    0.471
ISM_09641
Hypothetical protein; COG3591 V8-like Glu-specific endopeptidase; Belongs to the peptidase S1B family.
  
     0.461
ISM_10056
COG1977 Molybdopterin converting factor, small subunit.
  
     0.453
ISM_10426
COG3258 Cytochrome c.
   
 
  0.426
ISM_16090
Acyltransferase, putative; COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase.
  
   
 0.418
leuC
Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
       0.417
leuD
Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
       0.417
ISM_16095
Hypothetical protein; COG3176 Putative hemolysin.
  
     0.413
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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