STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ISM_08015COG2249 Putative NADPH-quinone reductase (modulator of drug activity B). (241 aa)    
Predicted Functional Partners:
ISM_17225
Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components.
 
 
 0.907
ISM_00255
Tryptophan repressor binding protein; COG0655 Multimeric flavodoxin WrbA.
 
  
 0.807
ISM_08800
NAD(P)H dehydrogenase, quinone family protein; COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).
  
  
  0.748
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
     
  0.595
ISM_14290
COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases; Belongs to the complex I 20 kDa subunit family.
    
   0.569
ISM_08020
Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
       0.547
ISM_02335
Methyltransferase, UbiE/COQ5 family protein; COG0500 SAM-dependent methyltransferases.
     
  0.529
ISM_16570
2-heptaprenyl-1,4-naphthoquinone methyltransferase (menaquinonebiosynthesis methyltransferase); COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis.
     
  0.529
ISM_16925
Hypothetical protein; COG1226 Kef-type K+ transport systems, predicted NAD-binding component.
   
 
 0.402
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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