Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_08160Ammonium transporter; COG0004 Ammonia permease. (460 aa)    
Predicted Functional Partners:
ISM_05410
COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
 0.972
ISM_08965
COG0347 Nitrogen regulatory protein PII.
 
 0.963
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
 
  
 0.767
ISM_08155
Flavin-containing monooxygenase; COG2072 Predicted flavoprotein involved in K+ transport.
 
     0.767
ISM_16640
Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific.
  
 
 0.714
ISM_08185
Hypothetical protein.
 
     0.635
ISM_08175
Hypothetical protein.
 
     0.616
ISM_08170
Aminomethyltransferase; COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family.
 
   
 0.564
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
    
 0.551
ISM_15340
GXGXG motif-containing protein; COG0070 Glutamate synthase domain 3.
 
  
 0.542
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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