| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_04030 | ISM_08250 | ISM_04030 | ISM_08250 | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | COG3938 Proline racemase; Belongs to the proline racemase family. | 0.734 |
| ISM_04030 | ISM_08325 | ISM_04030 | ISM_08325 | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.789 |
| ISM_04030 | ISM_08700 | ISM_04030 | ISM_08700 | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.584 |
| ISM_04030 | proC | ISM_04030 | ISM_11120 | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.552 |
| ISM_04030 | proC-2 | ISM_04030 | ISM_15230 | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.552 |
| ISM_07495 | ISM_08250 | ISM_07495 | ISM_08250 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | COG3938 Proline racemase; Belongs to the proline racemase family. | 0.659 |
| ISM_07495 | ISM_08255 | ISM_07495 | ISM_08255 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | Dihydroxydipicolinate synthase family protein; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. | 0.570 |
| ISM_07495 | ISM_08325 | ISM_07495 | ISM_08325 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.619 |
| ISM_08240 | ISM_08245 | ISM_08240 | ISM_08245 | COG1012 NAD-dependent aldehyde dehydrogenases. | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.609 |
| ISM_08240 | ISM_08250 | ISM_08240 | ISM_08250 | COG1012 NAD-dependent aldehyde dehydrogenases. | COG3938 Proline racemase; Belongs to the proline racemase family. | 0.782 |
| ISM_08240 | ISM_08255 | ISM_08240 | ISM_08255 | COG1012 NAD-dependent aldehyde dehydrogenases. | Dihydroxydipicolinate synthase family protein; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. | 0.671 |
| ISM_08240 | ISM_08325 | ISM_08240 | ISM_08325 | COG1012 NAD-dependent aldehyde dehydrogenases. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.619 |
| ISM_08245 | ISM_08240 | ISM_08245 | ISM_08240 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | COG1012 NAD-dependent aldehyde dehydrogenases. | 0.609 |
| ISM_08245 | ISM_08250 | ISM_08245 | ISM_08250 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | COG3938 Proline racemase; Belongs to the proline racemase family. | 0.663 |
| ISM_08245 | ISM_08255 | ISM_08245 | ISM_08255 | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | Dihydroxydipicolinate synthase family protein; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. | 0.597 |
| ISM_08250 | ISM_04030 | ISM_08250 | ISM_04030 | COG3938 Proline racemase; Belongs to the proline racemase family. | COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.734 |
| ISM_08250 | ISM_07495 | ISM_08250 | ISM_07495 | COG3938 Proline racemase; Belongs to the proline racemase family. | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.659 |
| ISM_08250 | ISM_08240 | ISM_08250 | ISM_08240 | COG3938 Proline racemase; Belongs to the proline racemase family. | COG1012 NAD-dependent aldehyde dehydrogenases. | 0.782 |
| ISM_08250 | ISM_08245 | ISM_08250 | ISM_08245 | COG3938 Proline racemase; Belongs to the proline racemase family. | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.663 |
| ISM_08250 | ISM_08255 | ISM_08250 | ISM_08255 | COG3938 Proline racemase; Belongs to the proline racemase family. | Dihydroxydipicolinate synthase family protein; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. | 0.806 |