Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_08250COG3938 Proline racemase; Belongs to the proline racemase family. (341 aa)    
Predicted Functional Partners:
ISM_08255
Dihydroxydipicolinate synthase family protein; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family.
 
  
 0.810
ISM_08325
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
    
 0.798
ISM_08240
COG1012 NAD-dependent aldehyde dehydrogenases.
 
 
 0.779
ISM_06540
Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family.
     
  0.739
ISM_04030
COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog.
 
  
 0.729
ISM_08700
Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog.
 
  
 0.714
ISM_14525
COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog.
    
 0.670
ISM_08245
Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators.
 
     0.665
ISM_07495
Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases.
 
 
 0.655
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
 0.654
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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