STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_08260Type I secretion membrane fusion protein, HlyD family protein; COG0845 Membrane-fusion protein. (412 aa)    
Predicted Functional Partners:
ISM_00700
COG1538 Outer membrane protein.
  
 0.991
ISM_05600
Type I secretion outer membrane protein, TolC family protein; COG1538 Outer membrane protein.
  
 0.991
ISM_17455
COG1538 Outer membrane protein.
  
 0.991
lolD
Lipoprotein releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
  
 
 0.978
ISM_00695
Probable ATP-binding/permease fusion ABC transporter; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.
 0.943
ISM_08265
COG4618 ABC-type protease/lipase transport system, ATPase and permease components.
  
 0.913
ISM_04570
Transporter, AcrB/AcrD/AcrF family protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.862
ISM_06295
Cation/multidrug efflux pump, RND family protein; COG0841 Cation/multidrug efflux pump.
  
 0.862
ISM_08230
RND family efflux transporter; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.862
ISM_09386
Transporter, AcrB/AcrD/AcrF family protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.862
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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