Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_08310COG1012 NAD-dependent aldehyde dehydrogenases. (470 aa)    
Predicted Functional Partners:
ISM_11415
Hypothetical protein; COG1454 Alcohol dehydrogenase, class IV.
 
 0.977
ISM_08315
COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
  0.974
ISM_08305
COG3181 Uncharacterized protein conserved in bacteria.
 
     0.777
ISM_00165
Oxidoreductase, zinc-binding dehydrogenase family protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.
    
  0.702
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
  
 
 0.699
ISM_16740
Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins.
  
 0.696
ISM_10915
COG1012 NAD-dependent aldehyde dehydrogenases.
     
 0.695
ISM_05875
phenylacetate-CoA ligase, putative; COG1541 Coenzyme F390 synthetase.
   
 0.690
ISM_14750
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 0.685
xsc
Hypothetical protein; Catalyzes the degradation of sulfoacetaldehyde into sulfite and acetyl phosphate. Involved in sulfolactate degradation.
  
 
 0.683
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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