STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_08390HpcH/HpaI aldolase family protein; COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family. (257 aa)    
Predicted Functional Partners:
ISM_03980
Hydratase/decarboxylase family protein; COG3971 2-keto-4-pentenoate hydratase.
  
 
 0.891
ISM_10775
COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
 
 0.858
ISM_02625
Hypothetical protein; COG3232 5-carboxymethyl-2-hydroxymuconate isomerase.
  
  
 0.794
ISM_08395
COG0837 Glucokinase; Belongs to the bacterial glucokinase family.
       0.784
ISM_12500
Mandelate racemase/muconate lactonizing enzyme family protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
 
 0.579
ISM_09070
Hypothetical protein; COG3622 Hydroxypyruvate isomerase; Belongs to the hyi family.
  
  
 0.562
ISM_03680
Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases.
  
 
 0.531
ISM_03890
COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
  
 
  0.511
ISM_16580
6-phosphogluconate dehydrogenase domain protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
  
 
  0.511
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
       0.497
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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